Know thyself
I think that many people honestly try to know themselves, to know their inner self, to explore the depths of their heart, to know their own soul. If you try this... and you are like me in any way you just might find that what you find isn't always wonderful or good. If you are like me you will get to the point where you find that you need God, you need Jesus, you need to be given a new heart.
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Consider what we hear in this reading from John the Gentiles go to see Jesus. Philip and Andrew tell Jesus, "Hey, Lord there are some folks here to see you." Notice how Jesus responds. It almost seems rude what He does next.
If I were one of those Greeks I'd be scratching my head and wondering, "what does this have to do with me... all I wanted was to see you and chat with you?"
Yet Jesus wasn't ignoring them. He wasn't avoiding their request. Rather, He was offering a much more profound response than what they were expecting.
If we are looking for Jesus we need to look at the cross. The second reading (Hebrews 5:7-9) told us that Jesus learned obedience through what He suffered. In His suffering He obediently joined us in our suffering and became for us someone who can heal our broken hearts. God's greatest glory is to be found on the cross.
If we are looking for Jesus and if we find Him in His glory on the Cross we must imitate His openess, His love, His humility, and His self-gift. This is how the cross heals us. The grace of the cross is that it begins a new covenant where God no longer desires that we sacrifice to Him, as in the Old Testament, but rather now He sacrifices for us. We share in this sacrifice, in this new coventant [that we hear about in the first reading (Jeremiah 31:31-34)] we are given a new heart and we share in this sacrifice every time we approach the altar at mass. The new covenant in Jesus' blood is remembered and shared completely at each and every mass. It is in the Eucharist that we unite ourselves to Jesus' cross. It is in the Eucharist that we are healed.
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If you ever seek to "know thyself" and find that you then seek Jesus because you long for a new heart and a share in the new covenant then the only place to find Him and receive Him is on the cross and on the altar.